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Characterization and properties of alternative materials on electrode microstructures in biomedical applications B. S. Soto C1. , J. L. Sosa S1., E. Soto E.2, F. López H1., J. Vázquez S1., S. Alcántara I1. 1 Centro de Investigaciones en Dispositivos Semiconductores, 2Instituto de Fisiología. Benemérita Universidad Autónoma de Puebla. A. P. 1651, 72000 Puebla, México, [email protected] In the last decades, the study of cellular function and response has been used for understand the workings of the body. Electrical activity of cells has classically been studied using micropipette or planar microelectrodes, the difference and importance between these techniques mainly is the invasive and non-invasive monitoring of the electrical activity of cells. Typically, the micropipettes are made of glass, whereas the microelectrodes the possibilities are more ample: metals, indium-tin-oxide, iridium, silicon oxide, etc [1]. Another important point of planar electrodes is because by using a silicon substrate and standard integrated circuit fabrication is possible to develop a whole system in which the recording and the stimulation of cell activity are together. Additionally, the advance of the technology makes possible the growing of capabilities and sensitivity of cellular studies as well as the alternative for electrodes fabrication. In this sense, the study of microelectrode properties has been justify, firstly because a novel material could make possible new applications and second because the electrical characteristics are connected closely with the materials of which are made. To develop these materials we have to consider not only the electrical properties but also the biocompatibility. The focus of this work is to study the electrical properties and biocompatibility of metalo-phtalocyanine of different compounds in order to be used for biomedical applications. We obtain the I-V characteristics as well as the impedance measurements. The morphological studies was done for determinate the toxicity of the material. The comparison between the results from the alternative materials and typical once was important for validation of the selection of our material. The obtained results verify that the metalo-phtalocyanine is a biocompatible alternative material with good electrical properties for biomedical applications. 1. Fromherz, P., Offenh A., Vetter T. and Weis J., “A neuron-silicon: a retzius cell of the leech on an insulated-gate Field-effect Transistor”, Science, 252:1290-1293 (1991). * Agradecimiento: CONACyT y PROMEP
