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Mª JESUS LARRIBA
Bibliografía para la clase “Adhesión Celular y Cáncer: E-cadherina”
Adhesión celular:
Jamora C and Fuchs E (2002) Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol
4:E101-E108.
Pérez-Moreno M, Jamora C and Fuchs E (2003) Sticky business: orchestrating cellular signals at
adherens junctions. Cell 112:535-548.
Cavallaro U and Christofori G (2004) Cell adhesion and signalling by cadherins and Ig-CAMs in
cancer. Nat Rev Cancer 4:118-132.
Niessen CM (2007) Tight junctions/adherens junctions: basic structure and function. J Invest
Dermatol 127:2525-2532.
Pokutta S and Weis WI (2007) Structure and mechanism of cadherins and catenins in cell-cell
contacts. Annu Rev Cell Dev Biol 23:237-261
Inactivación funcional de E-cadherina en cáncer:
Berx G, Becker KF, Höfler H and van Roy F (1998) Mutations of the human E-cadherin (CDH1)
gene. Hum Mutat 12:226-237.
Christofori G and Semb H (1999) The role of the cell-adhesion molecule E-cadherin as a tumoursuppressor gene. Trends Biochem Sci 24:73-76.
Conacci-Sorrell M, Zhurinsky J and Ben-Ze'ev A (2002) The cadherin-catenin adhesion system in
signaling and cancer. J Clin Invest 109:987-991.
Strathdee G (2002) Epigenetic versus genetic alterations in the inactivation of E-cadherin. Semin
Cancer Biol 12:373-379.
Peinado H, Portillo F and Cano A (2004) Transcriptional regulation of cadherins during development
and carcinogenesis. Int J Dev Biol 48:365-375.
Transición Epitelio-Mesénquima:
Barrallo-Gimeno A and Nieto MA (2005) The Snail genes as inducers of cell movement and survival:
implications in development and cancer. Development 132:3151-3161.
De Craene B, van Roy F and Berx G (2005) Unraveling signalling cascades for the Snail family of
transcription factors. Cell Signal 17:535-547.
Thiery JP and Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions.
Nat Rev Mol Cell Biol 7:131-142.
Yang J, Mani SA and Weinberg RA (2006) Exploring a new twist on tumor metastasis. Cancer Res
66:4549-4552.
Peinado H, Olmeda D and Cano A (2007) Snail, Zeb and bHLH factors in tumour progression: an
alliance against the epithelial phenotype?. Nat Rev Cancer 7:415-428.
Radisky DC and LaBarge MA (2008) Epithelial-mesenchymal transition and the stem cell phenotype.
Cell Stem Cell 2:511-512.
Yang J and Weinberg RA (2008) Epithelial-mesenchymal transition: at the crossroads of development
and tumor metastasis. Dev Cell 14:818-829.
Polyak K and Weinberg RA (2009) Transitions between epithelial and mesenchymal states:
acquisition of malignant and stem cell traits. Nat Rev Cancer 9:265-273.
Thiery JP, Acloque H, Huang RYJ and Nieto MA (2009) Epithelial-mesenchymal transitions in
development and disease. Cell 139:871-890.
Brabletz S and Brabletz T (2010) The ZEB/miR-200 feedback loop--a motor of cellular plasticity in
development and cancer? EMBO Rep 11:670-677.
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